AI and the World's Hard Problems · Medicine & drug discovery · Nature (machine learning) · 2026-10-12
Machine learning analysis of cilia driven particle transport distinguishes primary ciliary dyskinesia from normal cilia
Primary ciliary dyskinesia (PCD) is a genetic condition with dysmotile cilia, and diagnosis remains challenging. The authors developed CiliaTracks, a machine learning framework that analyses particle transport on cultured airway cells captured by high-speed microscopy. Classical machine learning models and a convolutional neural network classified recordings from 14 PCD individuals and 10 healthy donors with 95-97% accuracy.