Machine learning-based multiclass classification of cognitive decline using ACE-III assessment data: a comparative study with SHAP explainability
Dementia and its earlier stages, mild cognitive impairment (MCI) and subjective cognitive decline (SCD), are increasingly common, yet automated tools that distinguish all four cognitive states simultaneously remain rare. The researchers developed and benchmarked twelve machine learning classifiers spanning linear, kernel-based, tree-based, boosting, probabilistic, distance-based and ensemble meta-learning paradigms for four-class cognitive stratification.
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