AI and the World's Hard Problems · Life sciences · Microsoft Research · 2026-09-29
Introducing Quine: An AI research system designed for the complexity of biology
Microsoft Research's Quine is an early-stage effort to build a multimodal world model of biology and an interactive harness that connects models, scientific tools, literature, and researchers, helping scientists prioritize hypotheses before lab testing. In collaboration with researchers at the Broad Institute of Harvard and MIT, the team used it to prioritize compounds predicted to drive therapeutic tumor-state shifts and validated several top-ranked candidates across multiple wet-lab assays. The system is experimental, intended for research only, and its outputs require review by qualified researchers.